|
KMID : 1143620140180010140
|
|
Korean Journal of Nuclear Medicine Technology
2014 Volume.18 No. 1 p.140 ~ p.144
|
|
|
Comparing the Change in SUVmax Over Time by the Type of Ductal Breast Carcinoma
|
|
Hyoung Mi-Jin
Kim Jeong-Nip
Moon Pyeong-Soo
Kim Kil-Hwan
|
|
|
Abstract
|
|
|
Purpose: The recent surge in breast carcinoma patients is reported in a variety of statistics. Breast cancer occurs mainly from duct and lobulus: 85% is from the breast ducts. The present study is aimed to distinguish the difference in SUVmax changing over time by identifying the type of cancers attacking from the duct.
Materials and Methods: The subjects of the study are 291 female breast cancer patients who have visited the present PET/CT center from July 1, 2012 to July 23, 2013. Based on the pathological results, 248 IDC (invasive ductal carcinoma) patients and 43 DCIS (ductal carcinoma in situ) patients were selected. In the same manner as the general PET/CT scan (3.7 MBq/Kg), F-FDG was injected, followed by the primary test (Routine tests) after 1 hr, and the secondary test (Delay test) after another hr. SUVmax was measured after setting ROI in the lesion based on the data from the two tests.
Results: As the comparative result of the change in the lesion SUVmax between the two groups, IDC group's SUVmax showed M=7.11 and SD=5.405 in the primary test and increased M=7.11 and SD=5.405 in the secondary test (P<0.05); DCIS group's SUVmax showed M=2.739, SD=1.229 in the primary test and increased M=2.614, SD=1.470 in the secondary test (P<0.05).
Conclusion: As the comparative result of SUVmax over time between the groups, IDC showed increased SUVmax in the secondary test (Delay test) compared to the primary test (Routine test) (P=0.000); DCIS showed decreased SUVmax in the secondary test (Delay test) compared to the primary test (Routine test) (P=0.039). It was confirmed through this study that the change in SUVmax has occurred over time by the type of breast cancer (IDC or DCIS) occurring from the breast
ducts. However, the onset of breast cancers (ILC, LCIS) from the lobulus was not discussed due to the lack of samples. Future research on the breast cancers from the lobulus is suggested.
|
|
|
KEYWORD
|
|
|
Duct, lobulus, Invasive ductal carcinoma, Ductal carcinoma in situ, Invasive lobular carcinoma, Lobular carcinoma in situ, Maximum Standard uptake value
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|